Hypoxia regulates the ferrous iron uptake and reactive oxygen species (ROS) level via divalent metal transporter 1 (DMT1) by hypoxia-inducible factor-1

Hypoxia regulates the ferrous iron uptak

Hypoxia regulates the ferrous iron uptake and reactive oxygen species level via divalent metal transporter 1 (DMT1) Exon1B by hypoxia-inducible factor-1

✍ Dan Wang; Li-Hong Wang; Yu Zhao; Ya-Peng Lu; Li Zhu 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 296 KB

## Abstract Hypoxia has been shown to increase the expression of a variety of proteins involved in iron homeostasis, including ceruloplasmin, transferrin, and transferring receptor. Divalent metal transporter 1 (DMT1) is a transmembrane protein that is important in divalent metal ion transport, in