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Hypoxia Regulates Osteoblast Gene Expression

✍ Scribed by Stephen M. Warren; Douglas S. Steinbrech; Babak J. Mehrara; Pierre B. Saadeh; Joshua A. Greenwald; Jason A. Spector; Pierre J. Bouletreau; Michael T. Longaker

Book ID: 115636370
Publisher: Elsevier Science
Year: 2001
Tongue: English
Weight: 285 KB
Volume: 99
Category: Article
ISSN: 0022-4804
DOI: 10.1006/jsre.2001.6128

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## Abstract Changes in regional oxygen tension that occur during skeletal development and fracture stimulate local bone cell activity to regulate bone formation, maintenance, and repair. The adaptive responses of bone cells to hypoxia are only beginning to be understood. The transcription factor hy