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Hypoxia Modulates HLA-G Gene Expression in Tumor Cells

✍ Scribed by Gaël Mouillot; Céline Marcou; Inès Zidi; Christine Guillard; Déborah Sangrouber; Edgardo D. Carosella; Philippe Moreau


Book ID
116531422
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
537 KB
Volume
68
Category
Article
ISSN
0198-8859

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HLA-G gene activation in tumor cells inv
✍ Gaël Mouillot; Céline Marcou; Philippe Rousseau; Nathalie Rouas-Freiss; Edgardo 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 French ⚖ 461 KB

The tissue distribution of HLA-G molecules is broader than originally reported in trophoblastic cells. On the basis of numerous studies, HLA-G is also expressed in malignant tumors and involved in tumor immune escape. The mechanisms of HLA-G gene regulation differ from those of classical HLA class I