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Hypoxia inducible factor-1α participate in dopaminergic differentiation from ES-derived neural stem cells

✍ Scribed by Tae-Sun Kim; Hideki Hida; Tadashi Masuda; Cha-Gyun Jung; Hitoo Nishino

Book ID
116775492
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
76 KB
Volume
58
Category
Article
ISSN
0168-0102

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## Abstract A reliable method to induce neural progenitor/stem cells (NPCs) into dopaminergic (DAergic) neurons has not yet been established. As well, the mechanism involved remains to be elucidated. To induce DAergic differentiation from NPCs, a cytokine mixture (C‐Mix) of interleukin (IL)‐1β, IL‐