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Hypoxia-inducible factor 1α and erythropoietin upregulation with deferoxamine salvage after neonatal stroke

✍ Scribed by Dezhi Mu; Yun Sil Chang; Zinaida S. Vexler; Donna M. Ferriero


Book ID
116458565
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
579 KB
Volume
195
Category
Article
ISSN
0014-4886

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Accumulating studies demonstrate that the expressions of hypoxia-inducible factor 1 (HIF-1), erythropoietin (EPO) and vascular endothelial growth factor (VEGF) depend on cellular oxygen tension, which is involved in the pathological process of tissue hypoxia and/or ischemia. The present study invest