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Hypoxia-inducible Factor 1 as one of the “Signaling Drivers” of Toll-like Receptor-Dependent and Allergic Inflammation

✍ Scribed by Vadim V. Sumbayev; Sally A. Nicholas


Publisher
Springer
Year
2010
Tongue
English
Weight
310 KB
Volume
58
Category
Article
ISSN
0004-069X

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## Abstract ## Objective To assess the presence of Toll‐like receptors (TLRs) 1–9 in human articular cartilage, and to investigate the effects of lipopolysaccharide (LPS)–induced activation of TLR‐4 on biosynthetic activity and matrix production by human articular chondrocytes. ## Methods TLRs 1