Hypoxia-induced Activation of Epidermal Growth Factor Receptor (EGFR) Kinase in the Cerebral Cortex of Newborn Piglets: The Role of Nitric Oxide
โ Scribed by Om Prakash Mishra; Qazi M. Ashraf; Maria Delivoria-Papadopoulos
- Publisher
- Springer
- Year
- 2010
- Tongue
- English
- Weight
- 312 KB
- Volume
- 35
- Category
- Article
- ISSN
- 0364-3190
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๐ SIMILAR VOLUMES
Previous studies have shown that hypoxia results in increased Ca 2ฯฉ influx in neuronal nuclei and generation of nitric oxide (NO) free radicals in the cerebral cortical tissue of newborn piglets. The present study tests the hypothesis that hypoxia results in modification of the inositol triphosphate
## Abstract Selective tyrosine kinase inhibitors are regarded as promising antitumor agents for cancer treatment. Iressaยฎ (ZD1839) is an orally active, selective EGFRโTKI (epidermal growth factor receptorโtyrosine kinase inhibitor) that blocks signal transduction pathways implicated in cancer cell