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Hypoxia increases cytosolic free calcium in porcine pulmonary arterial endothelial cells

โœ Scribed by Qing-hua, Hu ;Di-xun, Wang

Book ID
112927044
Publisher
Springer-Verlag
Year
1993
Tongue
English
Weight
410 KB
Volume
13
Category
Article
ISSN
0257-716X

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Exposure to hypoxia (0% O2) for 4-24 h resulted in increased intracellular L-arginine content and increased activity of calpain, a calcium-dependent neutral cysteine protease, in pulmonary artery endothelial cells. Calpain-inhibitor I abolished the increased L-arginine content in hypoxic cells. When