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Hypoxia increases 25-hydroxycholesterol-induced interleukin-8 protein secretion in human macrophages

✍ Scribed by Ellen Knutsen Rydberg; Linda Salomonsson; Lillemor Mattsson Hultén; Kristina Norén; Göran Bondjers; Olov Wiklund; Tom Björnheden; Bertil G Ohlsson

Book ID: 119435966
Publisher: Elsevier Science
Year: 2003
Tongue: English
Weight: 225 KB
Volume: 170
Category: Article
ISSN: 0021-9150
DOI: 10.1016/s0021-9150(03)00302-2

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## Abstract CXCL8 is a CXC chemokine that recruits leukocytes to sites of inflammation. Expression of CXCL8 in the CNS has been demonstrated in neuroinflammatory diseases, including human immunodeficiency virus (HIV‐1) encephalitis, but the mechanism of secretion of this chemokine is not fully unde