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Hypoxia and retinoic acid-inducible NDRG1 expression is responsible for doxorubicin and retinoic acid resistance in hepatocellular carcinoma cells

✍ Scribed by Eun Uk Jung; Jung-Hwan Yoon; Youn-Jae Lee; Jeong-Hoon Lee; Bo Hyun Kim; Su Jong Yu; Sun Jung Myung; Yoon Jun Kim; Hyo-Suk Lee

Book ID: 116335500
Publisher: Elsevier Science
Year: 2010
Tongue: English
Weight: 859 KB
Volume: 298
Category: Article
ISSN: 0304-3835
DOI: 10.1016/j.canlet.2010.05.020

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## Abstract Retinoic acid (RA) and its derivatives inhibit the proliferation of normal human mammary epithelial cells (HMEC) and some breast carcinoma lines by mechanisms which are not fully understood. To identify genes that mediate RA‐induced cell growth arrest, an HMEC cDNA library was synthesiz