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Hypoxia and oxidative stress in breast cancer: Hypoxia signalling pathways

โœ Scribed by Christopher W Pugh, Jonathan Gleadle, Patrick H Maxwell

Book ID
120700789
Publisher
BioMed Central
Year
2001
Tongue
English
Weight
58 KB
Volume
3
Category
Article
ISSN
1465-5411

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Hypoxia, a common consequence of solid tumor growth in breast cancer and other cancers, serves to propagate a cascade of molecular pathways which include angiogenesis, glycolysis, and alterations in microenvironmental pH. Hypoxia-inducible factors, heterodimeric DNA binding complexes composed of two