Hypoxanthine-guanine phosphoribosyltransferase variants: Correlation of clinical phenotype with enzyme activity
✍ Scribed by T. Page; B. Bakay; E. Nissinen; W. L. Nyhan
- Book ID
- 105519321
- Publisher
- Springer
- Year
- 1981
- Tongue
- English
- Weight
- 442 KB
- Volume
- 4
- Category
- Article
- ISSN
- 0141-8955
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## Abstract Five clones of mouse neuroblastoma cells able to grow in hypoxanthine‐aminopterin‐thymidine containing medium were isolated from a hypoxanthine‐guanine phosphoribosyltransferase (HGPRT; EC 2.4.2.8; IMP: pyrophosphate phosphoribosyltransferase) deficient cell line. These hypoxanthine‐ami