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Hypothyroidism down-regulates mitochondrial citrate carrier activity and expression in rat liver

✍ Scribed by Anna M. Giudetti; Monica Leo; Luisa Siculella; Gabriele V. Gnoni


Book ID
116273069
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
269 KB
Volume
1761
Category
Article
ISSN
1388-1981

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## Abstract The citrate carrier (CiC), a nuclear‐encoded protein located in the mitochondrial inner membrane, is a member of the mitochondrial carrier family. CiC plays an important role in hepatic lipogenesis, which is responsible for the efflux of acetyl‐CoA from the mitochondria to the cytosol i