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Hypothesis: RNA polymerase: Structural determinat of the chromatin loop and the chromosome

✍ Scribed by Peter R. Cook

Book ID
102761928
Publisher
John Wiley and Sons
Year
1994
Tongue
English
Weight
975 KB
Volume
16
Category
Article
ISSN
0265-9247

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✦ Synopsis

Sumary

Current models for RNA synthesis involve an RNA polymerase that tracks along a static template. However, research on chromatin loops suggests that the template slides past a stationary polymerase; individua1 polymerases tie the chromatin fibre into loops and clusters of polymerases determine the basic structure of the interphase and metaphase chromosome. RNA polymerase is then both a player and a manager of the chromosome loop.

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