Molecular aspects of Huntington's diseas
✍
Hobart W. Walling; Joseph J. Baldassare; Thomas C. Westfall
📂
Article
📅
1998
🏛
John Wiley and Sons
🌐
English
⚖ 74 KB
Huntington's disease (HD) is a progressive neurodegenerative disease striking principally medium spiny GABAergic neurons of the caudate nucleus of the basal ganglia. It affects about one in 10,000 individuals and is transmitted in an autosomal dominant fashion. The molecular basis of the disease is