Hypothalamic-pituitary function and growth in children with intracranial lesions
✍ Scribed by R. Brauner; L. Adan; J. C. Souberbielle
- Publisher
- Springer
- Year
- 1999
- Tongue
- English
- Weight
- 38 KB
- Volume
- 15
- Category
- Article
- ISSN
- 0256-7040
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## Abstract We report on the hypothalamic‐pituitary‐gonadal function in 2 male infants with the Smith‐Lemli‐Opitz (SLO or RSH) syndrome. Both infants had abnormal external genitalia. Basal and LHRH stimulated plasma gonadotropins were normal for age (1 month). Plasma testosterone, androstenedione,
Weanling rats with ventromedial (VMNL) and dorsomedial (DMNL) hypothalamic lesions and sham-operated controls were maintained up t o 198 days after operation. Food intake was measured throughout the experiment and organ weights were recorded at various periods of sacrifice. Comparisons were made bet