Hypothalamic Integration of Circadian Rhythms

✍ Scribed by R.M. Buijs, A. Kalsbeek, H.J. Romijn, C.M.A. Pennartz and M. Mirmiran (Eds.)

• Publisher: Elsevier Science
• Year: 1996
• Tongue: English
• Leaves: 393
• Series: Progress in Brain Research 111
• Edition: 1
• Category: Library

✦ Synopsis

The International Summer School of Brain Research, on which this book is based, was organized by the Netherlands Institute for Brain research (NIBR), which has a rich history dating back to the beginning of the century.

The focus of interest in this present volume of Progress in Brain Research are the few thousand neurons at the base of the hypothalamus that form the biological clock. Attention is focused on the mechanisms underlying the generation of circadian rhythmicity within our biological clock, which is still far from understood. Contributions originating from many disciplines give updates on the latest theories on the molecular and electrophysiological basis of the pacemaker mechanism, and the various approaches used in different species. Attention is also paid to the way the signal of the biological clock is transferred to the rest of the central nervous system. New data on the role of the suprachiasmatic nucleus and its impact on the functioning of the human being is presented. Altogether an excellent volume which will further the understanding of this elusive material.

✦ Table of Contents

Content:
Editoral Page
Page iii

Copyright Page
Page iv

Preface
Pages ix-x
Ruud M. Buijs, A. Kalsbeek, M. Mirmiran, C.M.A. Pennartz, H.J. Romijn, T. Eikelboom, O. Pach, W. Top

List of Contributors
Pages v-viii

Acknowledgements
Page xi

The Sixth C.U. Ariëns Kappers Lecture
Pages 3-4

Chapter 1 The biological clock: it's all in the genes Original Research Article
Pages 5-9
Joseph S. Takahashi

Chapter 2 The genetic and molecular dissection of a prototypic circadian system Original Research Article
Pages 11-27
Jay C. Dunlap, Jennifer J. Loros, Martha Merrow, Susan Crosthwaite, Deborah Bell-Pedersen, Norman Garceau, Mari Shinohara, Hyeseon Cho, Chenghua Luo

Chapter 3 The Drosophila genes timeless and period collaborate to promote cycles of gene expression composing a circadian pacemaker Original Research Article
Pages 29-39
Michael W. Young

Chapter 4 Excitatory and inhibitory amino acids and synaptic transmission in the suprachiasmatic nucleus Original Research Article
Pages 41-56
Anthony N. van den Pol, George J. Strecker, F. Edward Dudek

Chapter 5 Astrocytes in the mammalian circadian clock: putative roles Original Research Article
Pages 57-73
J. Servière, M. Lavialle

Chapter 6 Circadian rhythms of neuropeptides in the suprachiasmatic nucleus Original Research Article
Pages 75-90
S.-I.T. Inouye

Chapter 7 Circadian rhythm generation, expression and entrainment in a molluscan model system Original Research Article
Pages 93-102
Gene D. Block, Michael Geusz, Sat Bir Khalsa, Stephan Michel, David Whitmore

Chapter 8 Entrainment pathways and the functional organization of the circadian system Original Research Article
Pages 103-119
Robert Y. Moore

Chapter 9 Regulation of entrainment pathways by the suprachiasmatic circadian clock: sensitivities to second messengers Original Research Article
Pages 121-132
Martha U. Gillette

Chapter 10 Light entrainment and activation of signal transduction pathways in the SCN Original Research Article
Pages 133-146
Jon M. Kornhauser, David D. Ginty, Michael E. Greenberg, Kelly E. Mayo, Joseph S. Takahashi

Chapter 11 Entrainment of the circadian clock Original Research Article
Pages 147-174
Michael H. Hastings, Jonathan D. Best, Francis J.P. Ebling, Elizabeth S. Maywood, Shaun McNulty, Irina Schurov, Dan Selvage, Philip Sloper, Karen L. Smith

Chapter 12 Light entrainment of the mammalian biological clock Original Research Article
Pages 175-190
J.H. Meijer, K. Watanabe, L. Dét`ri, M.J. de Vries, H. Albus, J.A. Treep, J. Schaap, W.J. Rietveld

Chapter 13 Regulation and integration in the mammalian circadian system Original Research Article
Pages 191-203
Martin R. Ralph, Mark W. Hurd, Junichi Takeuchi, Lucy Melo, Anuradha Mathur, Diego A. Golombek

Chapter 14 The role of melatonin and light in the human circadian system Original Research Article
Pages 205-216
Alfred J. Lewy, Robert L. Sack

Chapter 15 Perinatal development of human circadian rhythms Original Research Article
Pages 217-226
Majid Mirmiran, Simone Lunshof

Chapter 16 The anatomical basis for the expression of circadian rhythms: the efferent projections of the suprachiasmatic nucleus Original Research Article
Pages 229-240
R.M. Buijs

Chapter 17 Electrophysiology of suprachiasmatic nucleus projections to hypothalamic paraventricular nucleus neurons Original Research Article
Pages 241-252
Michael L.H.J. Hermes, Ruud M. Buijs, Leo P. Renaud

Chapter 18 SCN output drives the autonomic nervous system: with special reference to the autonomic function related to the regulation of glucose metabolism Original Research Article
Pages 253-272
K. Nagai, N. Nagai, K. Shimizu, S. Chun, H. Nakagawa, A. Niijima

Chapter 19 Rhythms of inhibitory and excitatory output from the circadian timing system as revealed by in vivo microdialysis Original Research Article
Pages 273-293
A. Kalsbeek, R.M. Buijs

Chapter 20 Circadian control of reproduction in the female rat Original Research Article
Pages 295-320
Eline M. van der Beek

Chapter 21 A ‘clock for all seasons’ in the human brain Original Research Article
Pages 321-342
Thomas A. Wehr

Chapter 22 Sleep regulation: relation to photoperiod, sleep duration, waking activity, and torpor Original Research Article
Pages 343-348
Alexander A. Borbély, Irene Tobler

Chapter 23 Biological rhythms in the human life cycle and their relationship to functional changes in the suprachiasmatic nucleus Original Research Article
Pages 349-368
D.F. Swaab, E.J.W. Van Someren, J.N. Zhou, M.A. Hofman

Chapter 24 The suprachiasmastic nucleus: the biological clock of all seasons Original Research Article
Pages 369-384
P. Pevet, B. Pitrosky, P. Vuillez, N. Jacob, R. Teclemariam-Mesbah, R. Kirsch, B. Vivien-Roels, N. Lakhdar-Ghazal, B. Canguilhem, M. Masson-Pevet

Subject Index
Pages 385-391