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Hyposialated 185 kDa CD45RA+ molecules attain a high concentration in B lymphoma cells and in activated human B cells

โœ Scribed by Y. Yu; R. Rabinowitz; A. Polliack; H. Ben-Bassat; M. Schlesinger

Book ID
114423086
Publisher
John Wiley and Sons
Year
2002
Tongue
English
Weight
254 KB
Volume
68
Category
Article
ISSN
0902-4441

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High CD40 membrane expression in AIDS-related lymphoma B cell lines is associated with the CD45RA+, CD45RO+, CD95+ phenotype and high levels of its soluble form in culture supernatants
โœ Paolo De Paoli; Marzia Cozzi; Rosamaria Tedeschi; Annunziata Gloghini; Anna Mari ๐Ÿ“‚ Article ๐Ÿ“… 1997 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 86 KB ๐Ÿ‘ 2 views

CD40 is a membrane glycoprotein expressed on normal and neoplastic B lymphocytes. Stimulation through CD40 regulates important cellular functions, but the effects depend on its membrane density. While extensive studies have characterized CD40 in non-Hodgkin lymphomas of immunocompetent individuals,