## Abstract Multiple sclerosis (MS) lesions have been shown by conventional methods to have major alterations in water and myelin lipid contents. To characterize these abnormalities more efficiently, NMR spectroscopy was used to evaluate water content by measuring relaxation times at 0.5 and 2.0 T.
Hypoperfusion of the cerebral white matter in multiple sclerosis: possible mechanisms and pathophysiological significance
โ Scribed by De Keyser, Jacques; Steen, Christel; Mostert, Jop P; Koch, Marcus W
- Book ID
- 109871100
- Publisher
- Nature Publishing Group
- Year
- 2008
- Tongue
- English
- Weight
- 169 KB
- Volume
- 28
- Category
- Article
- ISSN
- 0271-678X
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
Magnetic resonance imaging was used to evaluate the cerebral white matter of three subject groups: ( I ) 22 patients with known multiple sclerosis (MS) (1 1 with disease of shorter duration (0-5 years) and 11 with disease of longer duration (>5 years)); (2) 9 patients with suspected MS; and (3) 12 n
## Abstract Oxidative stress has been implicated in the pathophysiology of multiple sclerosis (MS). Increased levels of reactive oxygen species (ROS) derived from infiltrating macrophages and microglial cells have been shown to reduce the levels of endogenous antioxidants and to cause the oxidation