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Hypomethylation of Chromosome 1 Heterochromatin DNA Correlates with q-Arm Copy Gain in Human Hepatocellular Carcinoma

โœ Scribed by Nathalie Wong; Wai-Chun Lam; Paul Bo-San Lai; Elizabeth Pang; Wan-Yee Lau; Philip James Johnson


Book ID
117021205
Publisher
American Society for Investigative Pathology
Year
2001
Tongue
English
Weight
415 KB
Volume
159
Category
Article
ISSN
0002-9440

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## Abstract Recurrent chromosomal gain at 1q is one of the most common features of human hepatocellular carcinoma (HCC), but how the gain at 1q contributes to hepatocarcinogenesis is still unclear. To identify the target genes, precise determination of the shortest region of overlap (SRO) and of br