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Hypolipidemic activity of phthalimide derivatives. 7. Structure-activity studies of indazolone analogs

✍ Scribed by Wyrick, Steven D.; Voorstad, P. Josee; Cocolas, George; Hall, Iris H.


Book ID
120155589
Publisher
American Chemical Society
Year
1984
Tongue
English
Weight
573 KB
Volume
27
Category
Article
ISSN
0022-2623

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Electronic structure and hypolipidemic a
✍ Mozart N. Ramos; BenΓ­cio de B. Neto πŸ“‚ Article πŸ“… 1990 πŸ› John Wiley and Sons 🌐 English βš– 303 KB

## Abstract The hypolipidemic activities of phthalimide and seven related compounds are subjected to a QSAR analysis based on results from AM1 molecular orbital calculations. Least‐squares fits show a correlation of the activities with LUMO energies and carbonyl polarities and predict enhanced acti