We evaluated the effect of insulin on platelet function, blood viscosity, and filterability in healthy subjects and in patients with Type 2 (non-insulin-dependent) diabetes mellitus. Fifteen diabetic patients were free from cardiovascular complications (group A), while the other 15 patients had both
Hypolipidaemic Effect of Fenugreek Seeds: a Chronic Study in Non-insulin Dependent Diabetic Patients
โ Scribed by R. D. Sharma; A. Sarkar; D. K. Hazra; B. Misra; J. B. Singh; B. B. Maheshwari; S. K. Sharma
- Publisher
- John Wiley and Sons
- Year
- 1996
- Tongue
- English
- Weight
- 281 KB
- Volume
- 10
- Category
- Article
- ISSN
- 0951-418X
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โฆ Synopsis
The lipid lowering activity of fenugreek seeds (Trigonella foenum graecum L.) was studied in 60 non-insulin dependent diabetic subjects. Isocaloric diets without and with fenugreek were given for 7 days and 24 weeks respectively. Ingestion of an experimental diet containing 25 g fenugreek seed powder resulted in a significant reduction of total cholesterol, LDL and VLDL cholesterol and triglyceride levels. These results indicate the beneficial effect of fenugreek seeds in diabetic subjects.
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We analyzed by SSCP the complete IRS-1 coding sequence in NIDDM patient #25 D. Unique conformers corresponding to a Ser to Tyr substitution at codon 1043 (S1043Y), and to a Cys to Tyr substitution at codon 1095 (C1095Y) were detected in this patient. The results of sequential digestion with restrict