Hypokalemic periodic paralysis: electrophysiologic and contractile properties of intercostal muscle
✍ Scribed by R. Rüdel; G. Küther; K. Ricker; F. Lehmann-Horn; R. Dengler
- Book ID
- 115865558
- Publisher
- Elsevier Science
- Year
- 1983
- Tongue
- English
- Weight
- 119 KB
- Volume
- 56
- Category
- Article
- ISSN
- 0013-4694
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To study the mechanism of attacks in familial hypokalemic paralysis, we recorded resting membrane potentials, action potentials, currentvoltage relationships, and isometric forces in intercostal muscle fibers from three patients. In normal extracellular medium, the resting potential was reduced, but
## Abstract Electrophysiologic properties of biopsied normal and diseased intercostal muscle fibers were examined using intracellular microelectrode techniques. The resting potentials of all diseased muscle fibers were found to be depolarized. Those from Duchenne dystrophy patients showed the large