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HYPOGLYCAEMIA DUE TO AN INSULIN-RECEPTOR ANTIBODY IN HODGKIN'S DISEASE

✍ Scribed by Walters, EwanG.; Denton, RichardM.; Tavaré, JeremyM.; Walters, Glyn

Book ID
122362567
Publisher
The Lancet
Year
1987
Tongue
English
Weight
627 KB
Volume
329
Category
Article
ISSN
0140-6736

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Severe hypoglycaemia developed seven months after a bone marrow transplantation in a child with severe combined immunodeficiency. His serum exerted potent insulin-like activity: (a) it stimulated insulin receptor autophosphorylation and kinase activity in cell-free systems, this effect being additiv