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Hypocalcemic effect of salmon calcitonin following single and repeated nasal and intravenous administration in young rabbits

โœ Scribed by N. G. M. Schipper; S. G. Romeijn; J. Verhoef; F. W. H. M. Merkus

Publisher
Springer
Year
1994
Tongue
English
Weight
629 KB
Volume
54
Category
Article
ISSN
1432-0827

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Deacetyl diltiazem (M 1 ) is a major metabolite of the widely used calcium antagonist diltiazem (DTZ). In order to study the pharmacokinetic and haemodynamic effects of this metabolite, M 1 was administered as a single 5 mg kg -1 dose intravenously (iv) to New Zealand white rabbits (n = 5) via a mar