Hypertrophy of the rat urinary bladder following reduction of its functional volume
β Scribed by Peterson, Christine M. ;Goss, Richard J. ;Atryzek, Vladimir
- Publisher
- John Wiley and Sons
- Year
- 1974
- Tongue
- English
- Weight
- 217 KB
- Volume
- 187
- Category
- Article
- ISSN
- 0022-104X
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β¦ Synopsis
Abstract
If the functional volume of the rat urinary bladder is reduced by injecting varying quantities of a 50:50 melted mixture of paraffin and vaseline, the capacity of the bladder increases so as to provide the extra space needed to accommodate for the storage of urine. By four weeks, such bladders were found to have hypertrophied roughly in proportion to the size of the bolus of paraffinβvaseline they contained.
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## Abstract ## Aims We investigated the effects of 24β and 48βhr storage at 4Β°C in Krebs solution on the function and morphology of isolated, rat urinary bladders. ## Methods Strips of bladder were obtained from eight male SpragueβDawley rats. Six strips were harvested from each bladder and rand
We reported previously that substances in interstitial cystitis urine, when infused into the rabbit bladder, induce changes that resemble bladders of interstitial cystitis (IC) patients. Here we report our investigation of the effect of additional molecular weight subfractions of IC urine and lower