Astrocytic hypertrophy in dysmyelination
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Laura A. Harsan; Patrick Poulet; Blandine Guignard; Nathalie Parizel; Robert P.
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Article
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2007
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John Wiley and Sons
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English
β 646 KB
## Abstract The effect of a proteolipid protein (PLP) mutation on the developing white matter anisotropy was examined by diffusion tensor magnetic resonance imaging (DTβMRI) in a noninvasive study of a mouse model of PelizaeusβMerzbacher disease (PMD). The jimpy PLP mutation in mice produces an irr