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Hypertrophic pulmonary osteoarthropathy without clubbing of the digits

✍ Scribed by Stephen Clarke; Leslie Barnsley; Matthew Peters; Lucy Morgan; Hans Van der Wall

Publisher
Springer
Year
2001
Tongue
English
Weight
61 KB
Volume
30
Category
Article
ISSN
0364-2348

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Mutations in the prostaglandin transport
Mutations in the prostaglandin transporter encoding gene SLCO2A1 Cause primary hypertrophic osteoarthropathy and isolated digital clubbing
✍ Wenke Seifert; Jirko KΓΌhnisch; Beyhan TΓΌysΓΌz; Christof Specker; Ad Brouwers; Den πŸ“‚ Article πŸ“… 2012 πŸ› John Wiley and Sons 🌐 English βš– 279 KB

Digital clubbing is usually secondary to different acquired diseases. Primary hypertrophic osteoarthropathy (PHO) is a rare hereditary disorder with variable digital clubbing as the most prominent feature, subperiosteal new bone formation, and arthropathy. Recently, mutations in the 15-hydroxy-prost