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Hypertonic Saline Treatment of Severe Hyperkalemia in Nonnephrectomized Dogs

✍ Scribed by Justin L. Kaplan; C. Andrew Eynon; William C. Dalsey; Leonard E. Braitman; Dawn Clas; Lawrence de Garavilla


Book ID
109274638
Publisher
John Wiley and Sons
Year
2000
Tongue
English
Weight
119 KB
Volume
7
Category
Article
ISSN
1069-6563

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7.5% Hypertonic saline4% Dextran-70 (HSD) is currently being evaluated in our laboratory as a resuscitation solution for the treatment of hypovolemia at a dose of 4 ml kg-' body weight. A few reports of dextran toxicity, particularly of the kidney, have been cited in the literature, so the present s

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## Abstract Clinical use of modern dextran solutions has been limited by concerns of anaphylactoid reactions. To assess the short‐term antigenic response to 7.5% hypertonic saline in 6% Dextran‐70 (HSD), sera were obtained from dogs involved in the acute and subacute toxicology testing of HSD and i