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Hyperthermic potentiation of cytotoxicity of Ro-07-0582 in multicell spheroids

โœ Scribed by Rajagopalan Sridhar; Robert Sutherland


Publisher
Elsevier Science
Year
1977
Tongue
English
Weight
483 KB
Volume
2
Category
Article
ISSN
0360-3016

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โœ G. Akel; P. Benard; P. Canal; G. Soula ๐Ÿ“‚ Article ๐Ÿ“… 1986 ๐Ÿ› Springer ๐ŸŒ English โš– 703 KB

The hypoxic cell radiosensitizer 2-[14C] misonidazole: 1-(2-nitro-1-imidazolyl)-3-methoxy-2-propanol (Ro 07-0582) MISO was administered to mice, control rats, and rats bearing chemically induced rhadbdomyosarcoma. The dose injected was 250 mg/kg and the delivered activity was 100 microCi/kg. Whole-b