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Hyperthermia suppresses the cytotoxicity of NK cells via down-regulation of perforin/granzyme B expression

✍ Scribed by Tomoaki Koga; Hideki Harada; Tea Seow Shi; Seiji Okada; Mary Ann Suico; Tsuyoshi Shuto; Hirofumi Kai

Book ID: 116291580
Publisher: Elsevier Science
Year: 2005
Tongue: English
Weight: 258 KB
Volume: 337
Category: Article
ISSN: 0006-291X
DOI: 10.1016/j.bbrc.2005.09.184

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## Abstract It is known that vitamin C induces apoptosis in several kinds of tumor cells, but its effect on the regulation of the angiogenic process of tumors is not completely studied. Vascular endothelial growth factor (VEGF) is the most well‐known angiogenic factor, and it has a potent function