Two human melanoma cell lines (one radiosensitive, HT144 and one radioresistant, SK Mel-3) and one normal human fibroblast (AG1522) were evaluated for thermal radiosensitization and the thermal enhancement ratios (TERs) were calculated. These were compared with residual polymerase activity to determ
โฆ LIBER โฆ
Hyperthermia radiosensitization in human glioma cells comparison of recovery of polymerase activity, survival, and potentially lethal damage repair
โ Scribed by G.Peter Raaphorst; Mark M. Feeley
- Publisher
- Elsevier Science
- Year
- 1994
- Tongue
- English
- Weight
- 889 KB
- Volume
- 29
- Category
- Article
- ISSN
- 0360-3016
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Current evidence suggest an important role for increased repair of drug-induced DNA damage as one of the major mechanisms involved in tumor cell resistance to cis-DDP. In this study, we examined the DNA repair capacity and the activities of three DNA repair related proteins, namely, DNA polymerases