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Hypersensitivity reactions to mAbs: 105 desensitizations in 23 patients, from evaluation to treatment

โœ Scribed by Brennan, Patrick J.; Bouza, Tito Rodriguez; Hsu, F. Ida; Sloane, David E.; Castells, Mariana C.


Book ID
119282547
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
378 KB
Volume
124
Category
Article
ISSN
1097-6825

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Carboplatin is the drug of choice for the treatment of nonresectable astrocytomas in children, but patients who are intolerant may require cranial irradiation which is associated with significant morbidity. Hypersensitivity reactions, including urticaria, bronchospasm, and hypotension, have been rep