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Hypersensitivity reactions to deoxycoformycin

✍ Scribed by Peter J. O'Dwyer; Susan A. King; Elizabeth Eisenhauer; Jean L. Grem; Daniel F. Hoth

Publisher
Springer
Year
1989
Tongue
English
Weight
304 KB
Volume
23
Category
Article
ISSN
0344-5704

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✦ Synopsis

Deoxycoformycin (dCF) is a promising new antineoplastic agent in the treatment of lymphoid malignancies, particularly hairy cell leukemia (HCL). Skin toxicity in the form of a maculopapular eruption has previously been reported but has not clearly been associated with idiosyncratic reactions. We present five cases of dCF-related hypersensitivity reactions in which additional systemic manifestations indicated an allergic etiology. The value of dCF in treating lymphoid neoplasms suggests that further study of the treatment of these reactions is indicated.

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Hypersensitivity and idiosyncratic react
Hypersensitivity and idiosyncratic reactions to oxaliplatin
✍ Rebecca R. Thomas; Mary G. Quinn; Barbara Schuler; Jean L. Grem πŸ“‚ Article πŸ“… 2003 πŸ› John Wiley and Sons 🌐 English βš– 152 KB

## Abstract ## BACKGROUND Oxaliplatin is a third‐generation platinum analog that is used to treat a variety of solid tumors, particularly colorectal carcinoma. Patients may develop hypersensitivity reactions, although this complication occurs infrequently. ## METHODS Three patients developed hyp