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Hyperphosphorylation of Tau Induces Local Polyproline II Helix†

✍ Scribed by Bielska, Agata A.; Zondlo, Neal J.

Book ID
115448394
Publisher
American Chemical Society
Year
2006
Tongue
English
Weight
321 KB
Volume
45
Category
Article
ISSN
0006-2960

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The left-handed polyproline II helix (PPII) is believed to be the preferred conformation for proline-rich regions of sequence in proteins. Such regions have been postulated to be protein-protein interaction domains. The formation of this structure is studied here using simple Monte Carlo computer si