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Hyperphosphorylation of tau by deregulated Cdk5 (Cdk5/p25) activity is inhibited by its truncated activator (p35)

✍ Scribed by Varsha Shukla; Harish C. Pant

Book ID: 116779183
Publisher: Elsevier Science
Year: 2011
Tongue: English
Weight: 112 KB
Volume: 71
Category: Article
ISSN: 0168-0102
DOI: 10.1016/j.neures.2011.07.804

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## Abstract Although protein kinase Cdk5–p35 is important in many aspects of the development and function of the central nervous system, relatively little is known about its regulation. In the present study, we examined the relationship between the association of this kinase with membranes and its