Endomorphins: potential roles and therap
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Wei X. Liu; Rui Wang
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Article
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2011
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John Wiley and Sons
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English
⚖ 856 KB
The application of endomorphins as clinical available analgesic drugs has been impeded by their relatively poor receptor selectivity compared with alkaloid analgesics, rapid degradation in vivo, inefficient to penetrate the blood-brain barrier (BBB), and undesirable or toxic effects, such as acute t