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Hypermethylation of the neurofibromatosis type 1 (NF1) gene promoter is not a common event in the inactivation of the NF1 gene in NF1-specific tumours

✍ Scribed by Martin P. Horan; David N. Cooper; Meena Upadhyaya


Publisher
Springer
Year
2000
Tongue
English
Weight
300 KB
Volume
107
Category
Article
ISSN
0340-6717

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The gene responsible for von Recklinghausen neurofibromatosis (NF1) has recently been identified, and several point mutations and deletions have been described. The availability of intron-exon boundaries of several exons of the NF1 gene facilitates the search for mutations in affected patients. We h