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Hypermethylation of RASSF1A CpG promoter region and deletion aberrations in 3p21.31 LUCA region in major epithelial tumors


Book ID
117659649
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
321 KB
Volume
38
Category
Article
ISSN
0959-8049

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Detailed deletion mapping of chromosome
โœ Satoshi Matsumoto; Fujio Kasumi; Goi Sakamoto; Masahiko Onda; Yusuke Nakamura; M ๐Ÿ“‚ Article ๐Ÿ“… 1997 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 205 KB ๐Ÿ‘ 2 views

Loss of heterozygosity (LOH) on 3p is frequent in human renal cell carcinomas, lung cancers, and breast cancers. To define the region(s) on 3p that harbor presumptive tumor suppressor gene(s) for breast cancer, we examined 196 primary breast tumors for their patterns of LOH at 22 microsatellite mark