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Hypermethylation of multiple genes as clonal markers in multicentric hepatocellular carcinoma

โœ Scribed by Nomoto, S; Kinoshita, T; Kato, K; Otani, S; Kasuya, H; Takeda, S; Kanazumi, N; Sugimoto, H; Nakao, A

Book ID
109999295
Publisher
Nature Publishing Group
Year
2007
Tongue
English
Weight
234 KB
Volume
97
Category
Article
ISSN
0007-0920

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## Abstract The current study was conducted to identify robust methylation markers and their combinations that may prove useful for the diagnosis of early hepatocellular carcinoma (HCC). To achieve this, we performed __in silico__ CpG mapping, direct sequencing and pyrosequencing after bisulfite tr