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Hypermethylation of growth Arrest DNA-damage-inducible gene 45 in non-small cell lung cancer and its relationship with clinicopathologic features

โœ Scribed by Yeon Kyung Na; Su Man Lee; Hae Sook Hong; Jae Bum Kim; Jae Yong Park; Dong Sun Kim

Publisher
Korean Society for Molecular and Cellular Biology
Year
2010
Tongue
English
Weight
290 KB
Volume
30
Category
Article
ISSN
1016-8478

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## Abstract Promoter methylation is an important mechanism in gene silencing and is a key epigenetic event in cancer development. __Homeobox A5__ (__HOXA5__) is a master regulator of the morphogenesis and cell differentiation to be implicated as a tumor suppressor gene in breast cancer, but its rol