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Hypermethylation and transcriptional downregulation of the CITED4 gene at 1p34.2 in oligodendroglial tumours with allelic losses on 1p and 19q

✍ Scribed by Tews, B; Roerig, P; Hartmann, C; Hahn, M; Felsberg, J; Blaschke, B; Sabel, M; Kunitz, A; Toedt, G; Neben, K


Book ID
110072294
Publisher
Nature Publishing Group
Year
2007
Tongue
English
Weight
440 KB
Volume
26
Category
Article
ISSN
0950-9232

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✍ Markus J. Riemenschneider; Julia Reifenberger; Guido Reifenberger πŸ“‚ Article πŸ“… 2008 πŸ› John Wiley and Sons 🌐 French βš– 670 KB

## Abstract Deletion of the short arm of chromosome 1 is common in oligodendroglial tumors and has been identified as a powerful molecular marker for response to radio‐ and chemotherapy as well as favorable prognosis. Here, we investigated a series of 59 human primary gliomas for aberrations of the