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Hyperinsulinemia but No Diabetes in Transgenic Mice Homozygously Expressing the Tyrosine Kinase-Deficient Human Insulin Receptor

โœ Scribed by Lihong Wang; Naoko Muromoto; Hideki Hayashi; Yasumasa Mitani; Hisanori Uehara; Keisuke Izumi; Yousuke Ebina


Book ID
115581199
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
257 KB
Volume
240
Category
Article
ISSN
0006-291X

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The axl tyrosine kinase receptor is aberrantly expressed on myeloid cells of many individuals afflicted with chronic myelogenous leukemia (CML) and other myeloid leukemias. Although previous studies demonstrated this kinase to have oncogenic potential, it is not known whether axl actively participat