Hyperinducibility of Ia Antigen on Astrocytes Correlates with Strain-Specific Susceptibility to Experimental Autoimmune Encephalomyelitis

Strain difference in susceptibility to e

Strain difference in susceptibility to experimental autoimmune encephalomyelitis between Albino Oxford and Dark Agouti rats correlates with disparity in production of IL-17, but not nitric oxide

✍ Djordje Miljkovic; Stanislava Stosic-Grujicic; Milos Markovic; Miljana Momcilovi 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 467 KB

Albino Oxford (AO) rats, unlike Dark Agouti (DA) rats are resistant to the induction of experimental autoimmune encephalomyelitis (EAE). The reason for the resistance could be some restraining mechanism preventing auto-aggressive cell activation at the level of draining lymph nodes (DLN) during the