Hyperhomocysteinemia and the MTHFR C677T mutation in Budd-Chiari syndrome
β Scribed by Xiao-Mei Li; Ying-Fei Wei; Hong-Ling Hao; Yu-Bin Hao; Li-Shan He; Jing-Dong Li; Bing Mei; Su-Yun Wang; Chao Wang; Jun-Xiang Wang; Jun-Zhen Zhu; Jin-Quan Liang
- Publisher
- John Wiley and Sons
- Year
- 2002
- Tongue
- English
- Weight
- 64 KB
- Volume
- 71
- Category
- Article
- ISSN
- 0361-8609
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π SIMILAR VOLUMES
Studies have reported an association between homozygosity for a variant form of the methylenetetrahydrofolate reductase (MTHFR) gene and risk for neural tube defects. Because of MTHFR's involvement with folate metabolism and evidence that maternal use of a multivitamin with folic acid in early pregn
The polymorphic mutation C677T in the gene of MTHFR is considered a risk mutation for spina bifida and vascular disease. Another common mutation on the MTHFR gene, A1298C, has also been described as another risk mutation. We studied the frequencies of these two mutations on DNA samples from healthy