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Hyperhomocysteinemia and the MTHFR C677T mutation in Budd-Chiari syndrome

✍ Scribed by Xiao-Mei Li; Ying-Fei Wei; Hong-Ling Hao; Yu-Bin Hao; Li-Shan He; Jing-Dong Li; Bing Mei; Su-Yun Wang; Chao Wang; Jun-Xiang Wang; Jun-Zhen Zhu; Jin-Quan Liang


Publisher
John Wiley and Sons
Year
2002
Tongue
English
Weight
64 KB
Volume
71
Category
Article
ISSN
0361-8609

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The polymorphic mutation C677T in the gene of MTHFR is considered a risk mutation for spina bifida and vascular disease. Another common mutation on the MTHFR gene, A1298C, has also been described as another risk mutation. We studied the frequencies of these two mutations on DNA samples from healthy