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Hyperglycemia is associated with enhanced gluconeogenesis in a rat model of permanent cerebral ischemia

โœ Scribed by Wang, Ya-Yu; Chen, Chun-Jung; Lin, Shih-Yi; Chuang, Yu-Han; Sheu, Wayne Huey-Herng; Tung, Kwong-Chung


Book ID
120431327
Publisher
Elsevier Science
Year
2013
Tongue
English
Weight
810 KB
Volume
367
Category
Article
ISSN
0303-7207

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## Abstract We evaluated a role of hypoxiaโ€inducible factorโ€1ฮฑ (HIFโ€1ฮฑ) and its downstream genes in acute hyperglycemiaโ€induced hemorrhagic transformation in a rat model of focal cerebral ischemia. Male Spragueโ€Dawley rats weighing 280โ€“300 g (n = 105) were divided into sham, 90 min middle cerebral