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Hyperglycemia inhibits liver fatty acid oxidation and increases triacylglycerol secretion in humans

✍ Scribed by S. Sidossis; B. Mittendorfer; E. Walser; D. Chinkes; R. Wolfe

Book ID
110557089
Publisher
Springer-Verlag
Year
1999
Tongue
English
Weight
140 KB
Volume
34
Category
Article
ISSN
0024-4201

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Diltiazem inhibits fatty acid oxidation
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The eects of diltiazem on fatty acid metabolism were measured in the isolated perfused rat liver and in isolated mitochondria. In the perfused rat liver diltiazem inhibited oxygen uptake and ketogenesis from endogenous substrates. Ketogenesis from exogenously supplied palmitate was also inhibited. T