Hyperglycaemic clamp test for diabetes risk assessment in IA-2-antibody-positive relatives of type 1 diabetic patients
✍ Scribed by E. Vandemeulebroucke; B. Keymeulen; K. Decochez; I. Weets; C. De Block; F. Féry; U. Van de Velde; I. Vermeulen; P. De Pauw; C. Mathieu; D. G. Pipeleers; F. K. Gorus; The Belgian Diabetes Registry
- Publisher
- Springer
- Year
- 2009
- Tongue
- English
- Weight
- 181 KB
- Volume
- 53
- Category
- Article
- ISSN
- 0012-186X
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## Abstract ## Background Islet cell antibodies (ICA) represent a heterogenous group of autoantibodies to diabetes‐associated antigens, including glutamic acid decarboxylase (GAD) and the IA‐2 protein. The objectives of the present study were to compare the prevalence of autoantibodies to known bi
We have followed-up 35 islet cell antibody-positive first degree relatives of patients with Type 1 (insulin-dependent) diabetes mellitus for an average of 1,300 days with sequential intravenous glucose tolerance tests. At the time of analysis and manuscript submission approximately half (18 of 35) h