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Hyperglycaemia Inhibits Thymidine Incorporation and Cell Growth via Protein Kinase C, Mitogen-Activated Protein Kinases and Nitric Oxide in Human Umbilical Vein Endothelium

✍ Scribed by Susana Rojas; Romina Rojas; Liliana Lamperti; Paola Casanello; Luis Sobrevia


Book ID
110109421
Publisher
John Wiley and Sons
Year
2003
Tongue
English
Weight
376 KB
Volume
88
Category
Article
ISSN
0958-0670

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Cell growth inhibition by all-trans reti
✍ Shino Nakagawa; Teruhiko Fujii; Goro Yokoyama; Marcelo G. Kazanietz; Hideaki Yam πŸ“‚ Article πŸ“… 2003 πŸ› John Wiley and Sons 🌐 English βš– 359 KB

## Abstract All‐trans retinoic acid (ATRA), a synthetic derivative of vitamin A, inhibits the growth of breast cancer cells. To elucidate the mechanism by which ATRA causes cell growth inhibition, we examined changes in cell cycle and intracellular signaling pathways, focusing on protein kinase C (