Hypereosinophilic syndrome in a trisomy 21 fetus
โ Scribed by Yasuki Kusanagi; Hiroshi Ochi; Keiichi Matsubara; Masaharu Ito
- Book ID
- 117192827
- Publisher
- Lippincott Williams and Wilkins
- Year
- 1998
- Tongue
- English
- Weight
- 316 KB
- Volume
- 92
- Category
- Article
- ISSN
- 0029-7844
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In a series of 374 families with Down syndrome progeny, structural chromosome rearrangements were detected in the parents of six children with regular trisomy. The aberrations were reciprocal translocations and inversions. In all three informative families, the parent who transmitted the extra chrom
The lymphocyte chromosomes of trisomy 21 Down syndrome patients and their parents in a random series of 374 families were analyzed, the objective being the identification of parental mosaicism. The numbers of parents in whom at least two trisomy 21 cells were detected were seven mothers and three fa
The idiopathic hypereosinophilic syndrome (IHS) is extremely rare in childhood and relationships of this syndrome with myeloproliferative diseases are controversial. We reported the observation of a 7-year-old girl suffering from an IHS with myelofibrosis. A clonal cytogenetic abnormality, trisomy 8